Figure 3.

Effect of PD98059 i.t. injection on the heat, cold and mechanical stimuli-induced nocifensive behavior in capsaicin-treated rats.A: Mean head-withdrawal latency to heat stimulus of the skin. B: Mean number of face-scratching episodes following acetone application on the skin. C: mean head-withdrawal threshold to mechanical stimulus of the skin. *: p<0.05, **: p<0.01. PD: PD98059, Veh for PD: vehicle for PD98059, Cap: capsaicin, Veh for Cap: vehicle for capsaicin.