 ResearchRole of acid-sensing ion channel 3 in sub-acute-phase inflammationYi-Tin Yen1,2 1 Institute of Biomedical Sciences, Academia Sinica, Taipei 115, Taiwan 2 Institute of Zoology, College of Life Science, National Taiwan University, Taipei 106, Taiwan 3 Department of Anatomy and Cell Biology, National Taiwan University College of Medicine, Taipei 100, Taiwan 4 Department of Neurology, National Taiwan University Hospital, Taipei 100, Taiwan
Molecular Pain 2009, 5:1doi:10.1186/1744-8069-5-1
Additional filesAdditional file 1: Inflammation-mediated hyperalgesia in the contralateral paws. A, Thermal hyperalgesia results of intraplantar inflammation. B, von Frey filament test results of intraplantar inflammation. C, Thermal hyperalgesia results of intramuscular inflammation. D, von Frey filament tests results of intramuscular inflammation. WT: ASIC3+/+ mice, n = 6 in each group. KO: ASIC3-/- mice, n = 6 in each group. *p < 0.05 compared to baseline latency. #p < 0.05 comparison between ASIC3+/+ and ASIC3-/- groups. Format: PDF Size: 18KB Download file This file can be viewed with: Adobe Acrobat Reader Additional file 2: Gene expression level in ASIC3+/+ DRG 2 days after induction of inflammation. A, Expression of ASIC3, Nav1.6, Nav1.7, Nav1.8, Nav1.9 and TRPV1 2 days after intraplantar carrageenan-induced inflammation in L5 DRG. B, Expression of ASIC3, Nav1.6, Nav1.7, Nav1.8, Nav1.9 and TRPV1 2 days after intramuscular inflammation induction in L4 DRG. *p < 0.05 compared with saline group of the same side. Format: PDF Size: 20KB Download file This file can be viewed with: Adobe Acrobat Reader |
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